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Danazol (Danocrine) is a synthetic steroid hormone used in treatment of endometriosis, fibrocystic breast disease, benign breast tumors, abnormally long periods, premenstrual syndrome, gynecomastia and hereditary angioedema. Danazol is a brand name for the generic active ingredient "danocrine". It is a synthetic derivative of the male hormone testosterone and has both androgenic and anti-estrogenic effects. Danazol is available in oral capsule form and is typically prescribed by a healthcare provider. Order Danazol (generic) to from Barr Laboratories at our online drugstore - Pharmacy XL. Buy generic Danazol 50mg pills, 100mg tablets, 200mg tablets online without prescription and free shipping here for a guaranteed low price at our online pharmacy specialized in affordable medications including women's health drugs for your comfort and wellbeing.
One interesting fact about danazol is that it was originally developed as a male contraceptive. During its early stages of development, researchers discovered that danazol had anti-estrogenic and androgenic effects, which made it suitable for use as a male contraceptive. However, further studies revealed that it caused significant side effects, including liver toxicity and mood changes, which led to its discontinuation as a male contraceptive. Another interesting aspect of danazol is that it has been studied for its potential in treating various other conditions, such as immune-mediated disorders, including idiopathic thrombocytopenic purpura (ITP), systemic lupus erythematosus (SLE), and angioedema associated with acquired C1 inhibitor deficiency. However, its use in these conditions is limited and carefully considered due to its side effect profile and the availability of alternative treatment options.
In endometriosis, danazol works by suppressing the growth of abnormal endometrial tissue outside the uterus, which can help alleviate symptoms such as pelvic pain and infertility. In fibrocystic breast disease, danazol is believed to reduce breast pain and tenderness by decreasing estrogen levels and inhibiting the growth of breast tissue. In hereditary angioedema, danazol helps to prevent episodes of swelling in various parts of the body by increasing levels of a protein called C1 inhibitor, which helps regulate the immune response.
Generic Danazol (Danocrine) slows production of the female hormone estrogen. Danocrine is a man-made steroid that has similar actions to androgens, or male sex hormones. Generic Danazol is a cost-saving medication prescribed by medical physicians worldwide! Like any medication, danazol may have potential side effects, and its use should be closely monitored by a healthcare provider. Common side effects of danazol may include weight gain, acne, oily skin, irregular menstrual periods, and changes in voice pitch. Danazol is also associated with more serious side effects such as liver toxicity, mood changes, and potential harm to a developing fetus during pregnancy. It is important to follow the prescribed dosage and frequency of danazol as directed by a healthcare provider and to report any concerning side effects promptly.
Danazol is also marketed in the USA/Canada and international as: Cyclomen, generic Danazol, Danatrol and Danocrine.
*Danazol® is manufactered by and the registered trademark of Barr Laboratories.
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Danazol (Danocrine)
Common use of Danazol (Danocrine)
Danazol is a synthetic steroid produced from ethisterone. This medication suppresses synthesis of gonadotrophic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by pituitary gland in men and women. In women this drug inhibits activity of the ovaries, ovulation, leads to atrophy of the endometrium. The medication is used to treat to treat endometriosis (associated with sterility), fibrocystic breast disease, to prevent attacks of inherited angioedema, benign breast tumors (fibro-cystic breast), menorrhagia (abnormally heavy and prolonged menstrual period), premenstrual syndrome, primary premature puberty, gynecomastia.
Danazol Dosage and direction
The common recommended dose of Danazol (Danocrine) in adults is 200-800 mg a day divided in 2-4 intakes. Treatment starts on the first day of the menstrual cycle. To treat severe endometriosis the initial daily dose is 400 mg, later the dose may be increased to 800 mg by your physician. Treatment continues for six months. In children with premature puberty the dose is 100-400 mg.
Precautions when using Danazol (Danocrine)
Cautiousness with the use of Danazol should be exercised in patients with diabetes mellitus, epilepsy, migraine. Use reliable and effective forms of contraception while you are on Danazol such as a condom or diaphragm with spermicide gel or inserts as hormonal forms of contraception may turn out non effective. Dose correction is needed in patients with diabetes. Take this drug according to the instructions of your doctor. Do not exceed the recommended dose. Women may need to start Danazol during their menstrual period. This medication may change results of some medical tests, inform your doctor if you take this medication. Do not start or stop this medication without approval of your doctor, continue to take it even if you do not notice immediate positive results of treatment. If your symptoms do not improve in two months inform your doctor.
Contraindications of Danazol (Danocrine)
Danazol (Danocrine) cannot be used in patients with hypersensitivity to Danazol or its components, in pregnant and breastfeeding women, porphyria (activity of liver transaminases increases), liver or kidney failure, chronic heart failure, thromboembolism, androgen producing tumor, vaginal bleeding of unknown origin.
Danazol Side effects
The most common side effects of Danazol (Danocrine) include signs of allergy (hives, rash, facial swelling, difficulty breathing) and also sudden numbness or weakness, angina, sudden cough, wheezing, rapid breathing, fast heart rate, sudden problems with vision, speech, or balance, confusion, swelling, feeling short of breath, rapid weight gain, headache, vision problems, ringing in the ears, dizziness, nausea, loss of appetite, dark urine, pain behind the eyes, stomach pain, jaundice.
Drug interactions with Danazol
Danazol increases effects of anticoagulants of cumarine series and derivatives of indandione such as the risk of bleeding. Danazol decreases effects of insulin and oral hypoglycemic drugs by affecting metabolism of carbohydrates, increasing blood sugar levels Danazol inhibits metabolism of carbamazepine and increase its blood levels increases blood concentrations of cyclosporine and tacrolimus hereby increasing risk of nephrotoxicity. Danazol also increases serum levels of glucagon.
Missed dose of Danazol (Danocrine)
Take the missed dose of Danazol as soon as you remember. If it is almost time of your next dose just skip the missed dose and return to your schedule. Do not double dose this medication to make up the missed dose.
Danazol Overdose
Danazol (Danocrine) is not likely to produce life-threating symptoms. The most common effects of overdose are weight gain, menstrual problems, increased acne or facial hair growth, breast changes.
Storage of Danazol tablets
Store Danazol pills (Danocrine) at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.
Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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