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Depakote
Generic Depakote (Divalproex)

Depakote (Divalproex) is used to heal seizure disorders, convulsions, to prevent migraine and treat acute manic episodes associated with bipolar disorder. Depakote is a brand name for the medication divalproex sodium, which is a medication used for the management of various neurological and psychiatric conditions. It contains valproic acid, which is believed to work by increasing the levels of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain, which helps to calm and stabilize nerve activity. Order Depakote (generic) as mood stabilizer drug (Divalproex Sodium) from Abbott at our online drugstore - Pharmacy XL. Buy Depakote 125mg, 250mg or 500mg tablets online without prescription and with free shipping here for a guaranteed low price at our online pharmacy specialized in affordable medications including muscle relaxants and seizure drugs like Depakote for your health, but with much cheaper prices than your traditional local drugstores…

One interesting aspect of Depakote is its use in the treatment of epilepsy. It is approved for the management of different types of seizures, including generalized seizures, partial seizures, and absence seizures. Depakote has been shown to be effective in reducing the frequency and severity of seizures in many patients with epilepsy, helping to improve their quality of life. Another interesting aspect of Depakote is its use in the management of bipolar disorder. Bipolar disorder is a mental health condition characterized by episodes of mania (elevated mood) and depression (low mood). Depakote has been shown to be effective in stabilizing mood swings, reducing the frequency and severity of manic episodes, and preventing or reducing the intensity of depressive episodes in patients with bipolar disorder.

Generic Depakote (divalproex sodium) affects chemicals in the body and brain. This is a type of medicine called a mood stabilizer. It is used for a variety of different health issues. Depakote is one of Abbott Laboratories' best-selling drugs mainly prescribed for seizures & countless off-label uses. Depakote is also used off-label in the treatment of other conditions, such as migraines, neuropathic pain, and aggressive behaviors associated with certain psychiatric disorders. However, its off-label use should be carefully monitored and guided by a qualified healthcare provider.

Like any medication, Depakote may have side effects. Common side effects of divalproex sodium include drowsiness, dizziness, tremor, weight gain, and gastrointestinal disturbances. It may also cause more serious side effects, such as liver toxicity, pancreatitis, and birth defects if used during pregnancy. Regular monitoring of liver function and other parameters may be necessary during Depakote treatment.

Depakote is also marketed in the United States, Europe and Canada as: Depakote ER, Depakote Sprinkles, generic Depakote, Valproate, and Divalproex.

*Depakote® is manufactured by the American pharmaceutical company Abbott Laboratories.

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Depakote (divalproex)


Common use of Depakote (Divalproex)

Depakote contains Divalproex sodium, the substance which interacts with certain substances in the brain and increases the concentration of gamma-aminobutyric acid (GABA), which is a neurtransmitter. The drug is used to treat seizure disorders, the manic phase of bipolar disorders, to prevent migraine headaches.

Depakote Dosage and direction
The recommended initial Depakote dose for treatment of acute mania due to bipolar disorder is 750 mg daily taken in divided doses. For prevention of migraines take 250 mg twice daily. To treat seizures take initial dose calculated as 10-15 mg/kg/day, the dose should be increased gradually by 5-10 mg/kg/day every week to achieve the desired effect. Do not exceed the recommended dose and follow all recommendations of your health care advisor. Drink plenty of water during treatment. Liver function should be controlled on a regular basis to avoid harmful effects. Swallow the pill whole, do not crush or chew it. Inform your doctor immediately if you suppose that the medication does not work properly to prevent seizures. Do not stop taking the medicine without your doctor's permission even if you feel better.

Precautions when using Depakote (Divalproex)
Life-threating hepatic failure may develop, this is most likely to occur in children under two years of age especially if they if they have a metabolic disorder or a brain disease causing mental impairment (multiple sclerosis, Huntington disease, Creutzfeldt-Jacob disease, a brain injury or infection). Liver failure symptoms include malaise, lethargy, weakness, facial edema, vomiting, anorexia. Depakote also may cause rare cases of pancreatitis resulting in fatalities, which may suddenly appear even after several years of treatment with Depakote. Dose adjustment is needed in the patients with a bleeding or blood clotting disorder, a history of brain disorder, head injury, or coma, a family history of a urea cycle disorder, a family history of infant deaths with unknown cause, HIV or CMV (cytomegalovirus) infection. Suicide thoughts are also possible during treatment with the drug.

Contraindications of Depakote (Divalproex)
The medication Depakote cannot be administered to the patients with hepatic diseases, significant hepatic dysfunction known urea cycle disorders.

Possible side effect of Depakote (Divalproex)
The most common reported Depakote side effects are: nausea, somnolence, dizziness, vomiting, asthenia, abdominal pain, dyspepsia, rash, diarrhea, weight loss, tremors, low fever, dark urine, clay-colored stools. In some cases alopecia (loss of hair), itching and sensitivity to sunlight occur. More rare but serious adverse reactions include pancreatitis, liver injury, and abnormal bleeding. Liver is more likely to occur in children. The risk increases when a patient is taking two more more anti-seizure drugs. Symptoms of damaged liver are malaise, weakness, jaundice, swelling in the face, vomiting, loss of appetite.

Drug interactions of Depakote
The following drugs may interact with Depakote: topiramate (Topamax), tolbutamide (Orinase), a blood thinner such as warfarin (Coumadin), aspirin or acetaminophen (Tylenol), clozapine (Clozaril, FazaClo), diazepam (Valium), zidovudine (Retrovir), meropenem (Merrem), rifampin (Rifadin, Rimactane, Rifater), ethosuximide (Zarontin), indomethacin (Indocin), nabumetone (Relafen), ibuprofen (Motrin, Advil), naproxen (Naprosyn, Aleve), diclofenac (Voltaren, Cataflam, Arthrotec), ketorolac (Toradol) and aspirin. Such medicines as warfarin or heparin if used concomitantly with Depakote may affect blood clotting and lead to abnormal bleeding. Aspirin and felbamate (Felbatol) reduce catabolism of Depakote and hereby increase its blood concentrations. On the contrary phenytoin (Dilantin), Rifampin (Rifadin; Rimactane), carbamazepine (Tegretol) reduce its blood concentrations. Absorptin of Depakote is reduced by Cholestyramine (Questran), therefore intake of Depakote should be separated by at least two hours before or six hours after doses of cholestyramine.

Depakote can significantly increase concentrations in blood of lamotrigine (Lamictal), zidovudine (AZT), ethosuximide (Zarontin), diazepam (Valium) and phenobarbital, thereby increasing their concentrations in blood.

Missed dose of Depakote (Divalproex)
Never take a double dose of this medication "Depakote". If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Depakote Overdose
Depakote overdose symptoms include weak pulse, drowsiness, shallow breathing, somnolence, heart block, loss of consciousness, and deep coma. In case of the suspected overdose contact your doctor immediately and seek for immediate medical attention.

Storage of Depakote
Store Depakote (Divalproex) at room temperature 15-30 C (59-86 F) away from moisture and heat.

Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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