Generic Prograf (Tacrolimus)
Prograf

Prograf (Tacrolimus) suppresses immune system of the body to avoid rejection of a transplanted heart, liver, or kidney. Order Prograf (Generic) immunosuppressant drug to block actions of certain blood cells (Tacrolimus) from Astellas Pharma at online pharmacy - Pharmacy XL. Buy Prograf 0.5mg and 1.0mg tablets for transplant treatment without prescription and free shipping here for a low price at our mail order pharmacy specialized in high quality generic drugs for an affordable and low price.

Prograf (Tacrolimus) is an immunosuppressant. It blocks the action of certain blood cells that can cause the body to reject transplanted organs. Generic Prograf is used together with other medicines to prevent your body from rejecting a heart, liver, or kidney transplant.

Generic Prograf may also be marketed as: Tacrolimus, Prograf, Advagraf, Protocip, Fujimycin.

*Prograf® is a registered trademark of Astellas Pharma.

Package
Price
Per Pills
Savings
Bonuses
0,5 mg x 10 pills
$50.34
$5.03
$0.00
Next orders 10% discount
0,5 mg x 20 pills
$80.74
$4.04
$19.80
Next orders 10% discount
0,5 mg x 30 pills
$109.24
$3.64
$41.70
Next orders 10% discount
0,5 mg x 60 pills
$197.59
$3.30
$103.80
Next orders 10% discount
0,5 mg x 90 pills
$265.99
$2.95
$187.20
Next orders 10% discount
Package
Price
Per Pills
Savings
Bonuses
1 mg x 10 pills
$70.29
$7.03
$0.00
Next orders 10% discount
1 mg x 20 pills
$113.04
$5.65
$27.60
Next orders 10% discount
1 mg x 30 pills
$151.99
$5.06
$59.10
Next orders 10% discount
1 mg x 60 pills
$273.59
$4.56
$148.20
Next orders 10% discount
1 mg x 90 pills
$369.54
$4.10
$263.70
Next orders 10% discount
Package
Price
Per Pills
Savings
Bonuses
5 mg x 10 pills
$448.39
$44.84
$0.00
Next orders 10% discount
5 mg x 20 pills
$747.64
$37.38
$149.20
Next orders 10% discount
Product Description

Common use of Prograf (Tacrolimus)
Prograf suppresses immune system and is used to prevent organ rejection after transplantation of heart, kidney, small bowel, bone marrow. Its active component is anhydrous tacrolimus. The drug binds to cytosolic protein (FKBP 12) and inhibits calcineurin hereby suppressing T-cell dependent immune response of the organism, formation of cytotoxic lymphocytes, proliferation of B cells depending on T-helpers, and formation of interleukin-2, -3 and γ-interferon.

Prograf Dosage and direction
The daily dose of Prograf should be divided in two intakes separated by twelve hours. The capsules should be taken immediately after taking them out from the blister packs with full glass of water on an empty stomach, or at least one hour before or 2-3 hours after a meal. Fatty food decreases absorption of the medication. Correction of the dose is needed inpatients with serious liver impairment.

Precautions when using Prograf (Tacrolimus)
Risk of caner and especially skin cancer and infectious diseases increases due to immune suppressing effect of Prograf. Avoid exposing yourself to direct sun rays. Blood cell count, kidney and liver unction should be monitored on a regular basis while taking this medication. Diabetes may develop especially in Hispanic or African-American patients. Do not take the medicine with a grapefruit juice. This medication can appear in breast milk and transfer through placenta which can be harmful to a baby. Breastfeeding should be stopped while on Prograf. Inform your doctor if you have kidney or liver diseases, high blood pressure, or if you have taken cyclosporine (Neoral, Sandimmune, Gengraf) within the day before.

Contraindications of Prograf (Tacrolimus)
Prograf cannot be administered in patients hypersensitive to tacrolimus, other macrolides, or or hydrogenated castor oil.

Possible side effects of Prograf
Side effects of Prograf are numerous and include arterial hypertension, hypotension, angina, stroke, tachycardia, arrhythmia, diarrhea, nausea, vomiting, abdominal pain, change of liver transaminases activity, constipation, anemia, easy bruising and bleeding, changes in clotting, kidney disorders and failure, hyperglycemia, hyperpotessemia, diabetes, seizures, pain in joints, miastenia, tremor, headache, vision changes, dizziness, depression, mental confusion, hallucinations, difficulty breathing, allergy, achne, photosensitivity, high risk of tumor formation, high body temperature, swelling of extremities, baldness. In case of bothersome and serious side effects seek immediate medical attention.

Drug interactions of Prograf
Prograf may slow down metabolism of Cyclosporine (Neoral, Sandimmune, Gengraf) thus increasing its toxicity. As Prograf is metabolized by cytochrome CYP 3A4, a concomitant use of medications affecting or being metabolized by this cytochrome may change Prograf levels in the blood (for example testosterone, cortisone). Tacrolimus binds to proteins of blood serum and and may change (mutually) effects of the medications with high affinity to serum proteins such as peroral anticoagulants, diabetic drugs or NSAIDs. Concomitant use of Prograf with neurotoxic or nephrotoxic medication may increase toxicity (aminoglycosides, inhibitors of DNA gyrase, vancomycin, co-trimoxazole, NSAIDs, ganciclovir or acyclovir). Avoid co-administration of Prograf with potassium-saving diuretics of medicines which contain potassium to avoid hyperpotassemia (Dyazide, Maxzide, amiloride, Moduretic, and spironolactone, Aldactone). Effects of vaccination may be decreased and use of live attenuated vaccines should be avoided. Inform your doctor about all drugs and herbal products you are taking.

Missed dose of Prograf
Never take a double dose of this medication "Prograf (Tacrolimus)". If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Prograf Overdose
In cases of accidental Prograf overdose the following symptoms were described: tremor, headache, nausea, vomiting, infection, rash, lethargy, increased urea nitrogen in blood and increased serum concentrations of creatinine and alanine transaminase (ALT).

Storage of Prograf (Tacrolimus)
Prograf should be stored at room temperature between 15-30 C (59-86 F).

Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.